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Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way

BACKGROUND: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient increases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an experimental probe of adrenal cortisol secretion. OBJECTIVE: This...

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Publicado en:Endocr Connect
Main Authors: Roelfsema, Ferdinand, Liu, Peter Y, Yang, Rebecca, Takahashi, Paul, Veldhuis, Johannes D
Formato: Artigo
Idioma:Inglês
Publicado: Bioscientifica Ltd 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424344/
https://ncbi.nlm.nih.gov/pubmed/32520721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-20-0211
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