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Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases

Effective treatments for neurodegenerative diseases need to be developed. MiR132 is abundantly expressed in the brain, and it modulates neuron morphology and plays a key role in maintaining neuron survival. Regulating miR132 can effectively improve the symptoms of Alzheimer’s disease. It can also re...

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Publicado en:Front Pharmacol
Autores principales: Su, Yu, Sun, Bixi, Gao, Xiaoshu, Dong, Xinyue, Fu, Lanbo, Zhang, Yingxin, Li, Zhulin, Wang, Yue, Jiang, Hongyu, Han, Bing
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424054/
https://ncbi.nlm.nih.gov/pubmed/32848773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01165
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