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Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders

Genistein has been reported to have antioxidant and neuroprotective activity. Despite encouraging in vitro and in vivo results, several disadvantages such as poor water solubility, rapid metabolism, and low oral bioavailability limit the clinical application of genistein. The aim of this study was t...

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Detalles Bibliográficos
Publicado en:Pharmaceutics
Main Authors: Rassu, Giovanna, Porcu, Elena Piera, Fancello, Silvia, Obinu, Antonella, Senes, Nina, Galleri, Grazia, Migheli, Rossana, Gavini, Elisabetta, Giunchedi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359056/
https://ncbi.nlm.nih.gov/pubmed/30597930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11010008
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