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Intranasal Drug Delivery of Olanzapine-Loaded Chitosan Nanoparticles

The aim of this study was to investigate olanzapine (OZ) systemic absolute bioavailability after intranasal (i.n.) administration in vivo to conscious rabbits. Furthermore, the study investigated the potential use of chitosan nanoparticles as a delivery system to enhance the systemic bioavailability...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Baltzley, Sarah, Mohammad, Atiquzzaman, Malkawi, Ahmad H., Al-Ghananeem, Abeer M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245419/
https://ncbi.nlm.nih.gov/pubmed/25142821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0189-5
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