LAG-3 and PD-1+LAG-3 inhibition promote anti-tumor immune responses in human autologous melanoma/T cell co-cultures

Despite the success of immunotherapy using checkpoint blockade, many patients with solid tumors remain refractory to these treatments. In human cancer, the experimental options to investigate the specific effects of antibodies blocking inhibitory receptors are limited and it is still unclear which c...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Gestermann, Nicolas, Saugy, Damien, Martignier, Christophe, Tillé, Laure, Fuertes Marraco, Silvia A., Zettl, Markus, Tirapu, Iñigo, Speiser, Daniel E., Verdeil, Grégory
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422827/
https://ncbi.nlm.nih.gov/pubmed/32850194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1736792
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