Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients

A major limiting factor in the success of immunotherapy is tumor infiltration by CD8(+) T cells, a process that remains poorly understood. In the present study, we characterized homing receptors expressed by human melanoma-specific CD8(+) T cells. Our data reveal that P-selectin binding and expressi...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Murray, Timothy, Fuertes Marraco, Silvia A., Baumgaertner, Petra, Bordry, Natacha, Cagnon, Laurène, Donda, Alena, Romero, Pedro, Verdeil, Grégory, Speiser, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150229/
https://ncbi.nlm.nih.gov/pubmed/28018343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00573
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