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Low Avidity T Cells Do Not Hinder High Avidity T Cell Responses Against Melanoma

The efficacy of T cells depends on their functional avidity, i. e., the strength of T cell interaction with cells presenting cognate antigen. The overall T cell response is composed of multiple T cell clonotypes, involving different T cell receptors and variable levels of functional avidity. Recentl...

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Vydáno v:Front Immunol
Hlavní autoři: Ioannidou, Kalliopi, Randin, Olivier, Semilietof, Aikaterini, Maby-El Hajjami, Hélène, Baumgaertner, Petra, Vanhecke, Dominique, Speiser, Daniel E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742971/
https://ncbi.nlm.nih.gov/pubmed/31555299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02115
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