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Inhibitory Receptors Beyond T Cell Exhaustion

Inhibitory receptors (iRs) are frequently associated with “T cell exhaustion”. However, the expression of iRs is also dependent on T cell differentiation and activation. Therapeutic blockade of various iRs, also referred to as “checkpoint blockade”, is showing ­unprecedented results in the treatment...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Fuertes Marraco, Silvia A., Neubert, Natalie J., Verdeil, Grégory, Speiser, Daniel E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481276/
https://ncbi.nlm.nih.gov/pubmed/26167163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00310
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