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Predicting the chemical space of fungal polyketides by phylogeny-based bioinformatics analysis of polyketide synthase-nonribosomal peptide synthetase and its modification enzymes

Fungal polyketide synthase (PKS)–nonribosomal peptide synthetase (NRPS) hybrids are key enzymes for synthesizing structurally diverse hybrid natural products (NPs) with characteristic biological activities. Predicting their chemical space is of particular importance in the field of natural product c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Minami, Atsushi, Ugai, Takahiro, Ozaki, Taro, Oikawa, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7421883/
https://ncbi.nlm.nih.gov/pubmed/32782278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70177-w
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