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Analysis of Intact and Dissected Fungal Polyketide Synthase-Nonribosomal Peptide Synthetase in vitro and in Saccharomyces cerevisiae
The widely found fungal iterative PKS-NRPS hybrid megasynthetases are highly programmed biosynthetic machines involved in the synthesis of 3- acyltetramic acids and related natural products. In vitro analysis of iterative PKS-NRPS have been hampered by the difficulties associated with obtaining pure...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950873/ https://ncbi.nlm.nih.gov/pubmed/20828130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107084d |
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