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Analysis of Intact and Dissected Fungal Polyketide Synthase-Nonribosomal Peptide Synthetase in vitro and in Saccharomyces cerevisiae

The widely found fungal iterative PKS-NRPS hybrid megasynthetases are highly programmed biosynthetic machines involved in the synthesis of 3- acyltetramic acids and related natural products. In vitro analysis of iterative PKS-NRPS have been hampered by the difficulties associated with obtaining pure...

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Библиографические подробности
Главные авторы: Xu, Wei, Cai, Xiaolu, Jung, Michael E., Yi, Tang
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950873/
https://ncbi.nlm.nih.gov/pubmed/20828130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107084d
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