The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver

We earlier showed that outside-in integrin signaling through POSTN-ITGAV interaction plays an important role in regulating adult hematopoietic stem cell (HSC) quiescence. Here, we show that Itgav deletion results in increased frequency of phenotypic HSCs in fetal liver (FL) due to faster proliferati...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Biswas, Atreyi, Roy, Irene M., Babu, Prathibha C., Manesia, Javed, Schouteden, Sarah, Vijayakurup, Vinod, Anto, Ruby John, Huelsken, Joerg, Lacy-Hulbert, Adam, Verfaillie, Catherine M., Khurana, Satish
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419718/
https://ncbi.nlm.nih.gov/pubmed/32735820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.06.022
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