The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver

We earlier showed that outside-in integrin signaling through POSTN-ITGAV interaction plays an important role in regulating adult hematopoietic stem cell (HSC) quiescence. Here, we show that Itgav deletion results in increased frequency of phenotypic HSCs in fetal liver (FL) due to faster proliferati...

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Detaylı Bibliyografya
Yayımlandı:Stem Cell Reports
Asıl Yazarlar: Biswas, Atreyi, Roy, Irene M., Babu, Prathibha C., Manesia, Javed, Schouteden, Sarah, Vijayakurup, Vinod, Anto, Ruby John, Huelsken, Joerg, Lacy-Hulbert, Adam, Verfaillie, Catherine M., Khurana, Satish
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419718/
https://ncbi.nlm.nih.gov/pubmed/32735820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.06.022
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