The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver

We earlier showed that outside-in integrin signaling through POSTN-ITGAV interaction plays an important role in regulating adult hematopoietic stem cell (HSC) quiescence. Here, we show that Itgav deletion results in increased frequency of phenotypic HSCs in fetal liver (FL) due to faster proliferati...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Biswas, Atreyi, Roy, Irene M., Babu, Prathibha C., Manesia, Javed, Schouteden, Sarah, Vijayakurup, Vinod, Anto, Ruby John, Huelsken, Joerg, Lacy-Hulbert, Adam, Verfaillie, Catherine M., Khurana, Satish
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419718/
https://ncbi.nlm.nih.gov/pubmed/32735820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.06.022
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items