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UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters
UTX, a H3K27me3 demethylase, plays an important role in mouse brain development. However, so little is known about the function of UTX in human neural differentiation and dendritic morphology. In this study, we generated UTX-null human embryonic stem cells using CRISPR/Cas9, and differentiated them...
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| Publicado en: | Stem Cell Reports |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7419705/ https://ncbi.nlm.nih.gov/pubmed/32679064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.06.015 |
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