An essential role for UTX in resolution and activation of bivalent promoters

Trimethylated histone H3 lysine 27 (H3K27me3) is linked to gene silencing, whereas H3K4me3 is associated with gene activation. These two marks frequently co-occupy gene promoters, forming bivalent domains. Bivalency signifies repressed but activatable states of gene expression and can be resolved to...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Dhar, Shilpa S., Lee, Sung-Hun, Chen, Kaifu, Zhu, Guangjing, Oh, WonKyung, Allton, Kendra, Gafni, Ohad, Kim, Young Zoon, Tomoiga, Alin S., Barton, Michelle Craig, Hanna, Jacob H., Wang, Zhibin, Li, Wei, Lee, Min Gyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856969/
https://ncbi.nlm.nih.gov/pubmed/26762983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1516
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