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A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Self-renewal and pluripotency are two fundamental characteristics of embryonic stem cells (ESCs) and are controlled by diverse regulatory factors, including pluripotent factors, epigenetic regulators and microRNAs (miRNAs). Although histone methyltransferases are key epigenetic regulators, whether a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lee, Sung-Hun, Chen, Tsai-Yu, Dhar, Shilpa S., Gu, Bingnan, Chen, Kaifu, Kim, Young Zoon, Li, Wei, Lee, Min Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159542/
https://ncbi.nlm.nih.gov/pubmed/27625395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw788
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