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A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Self-renewal and pluripotency are two fundamental characteristics of embryonic stem cells (ESCs) and are controlled by diverse regulatory factors, including pluripotent factors, epigenetic regulators and microRNAs (miRNAs). Although histone methyltransferases are key epigenetic regulators, whether a...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Lee, Sung-Hun, Chen, Tsai-Yu, Dhar, Shilpa S., Gu, Bingnan, Chen, Kaifu, Kim, Young Zoon, Li, Wei, Lee, Min Gyu
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159542/
https://ncbi.nlm.nih.gov/pubmed/27625395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw788
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