A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Self-renewal and pluripotency are two fundamental characteristics of embryonic stem cells (ESCs) and are controlled by diverse regulatory factors, including pluripotent factors, epigenetic regulators and microRNAs (miRNAs). Although histone methyltransferases are key epigenetic regulators, whether a...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Lee, Sung-Hun, Chen, Tsai-Yu, Dhar, Shilpa S., Gu, Bingnan, Chen, Kaifu, Kim, Young Zoon, Li, Wei, Lee, Min Gyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159542/
https://ncbi.nlm.nih.gov/pubmed/27625395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw788
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