A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Self-renewal and pluripotency are two fundamental characteristics of embryonic stem cells (ESCs) and are controlled by diverse regulatory factors, including pluripotent factors, epigenetic regulators and microRNAs (miRNAs). Although histone methyltransferases are key epigenetic regulators, whether a...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Lee, Sung-Hun, Chen, Tsai-Yu, Dhar, Shilpa S., Gu, Bingnan, Chen, Kaifu, Kim, Young Zoon, Li, Wei, Lee, Min Gyu
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159542/
https://ncbi.nlm.nih.gov/pubmed/27625395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw788
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