UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters

UTX, a H3K27me3 demethylase, plays an important role in mouse brain development. However, so little is known about the function of UTX in human neural differentiation and dendritic morphology. In this study, we generated UTX-null human embryonic stem cells using CRISPR/Cas9, and differentiated them...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Tang, Qing-Yuan, Zhang, Shuang-Feng, Dai, Shang-Kun, Liu, Cong, Wang, Ying-Ying, Du, Hong-Zhen, Teng, Zhao-Qian, Liu, Chang-Mei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419705/
https://ncbi.nlm.nih.gov/pubmed/32679064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.06.015
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak