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Transcriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape

The transcriptional error rate can be significantly increased by the presence of DNA lesions that instruct mis-insertion during transcription; a process referred to as transcriptional mutagenesis (TM) that can result in altered protein function. Herein, we determined the effect of O(6)-methylguanine...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Liang, Shuo, Ezerskyte, Monika, Wang, Jingwen, Pelechano, Vicent, Dreij, Kristian
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419513/
https://ncbi.nlm.nih.gov/pubmed/32782319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70412-4
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