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Transcriptional mutagenesis reduces splicing fidelity in mammalian cells
Splicing fidelity is essential to the maintenance of cellular functions and viability, and mutations or natural variations in pre-mRNA sequences and consequent alteration of splicing have been implicated in the etiology and progression of numerous diseases. The extent to which transcriptional errors...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499639/ https://ncbi.nlm.nih.gov/pubmed/28460122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx339 |
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