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Post-transcriptional homeostasis and regulation of MCM2–7 in mammalian cells
The MiniChromosome Maintenance 2-7 (MCM2-7) complex provides essential replicative helicase function. Insufficient MCMs impair the cell cycle and cause genomic instability (GIN), leading to cancer and developmental defects in mice. Remarkably, depletion or mutation of one Mcm can decrease all Mcm le...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367205/ https://ncbi.nlm.nih.gov/pubmed/22362746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks176 |
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