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Role of transcript and interplay between transcription and replication in triplet-repeat instability in mammalian cells

Triplet-repeat expansions cause several inherited human diseases. Expanded triplet-repeats are unstable in somatic cells, and tissue-specific somatic instability contributes to disease pathogenesis. In mammalian cells instability of triplet-repeats is dependent on the location of the origin of repli...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rindler, Paul M., Bidichandani, Sanjay I.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025579/
https://ncbi.nlm.nih.gov/pubmed/20843782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq788
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