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Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

The effects of diverse stresses on promoter selectivity and transcription regulation by the tumor suppressor p53 are poorly understood. We have taken a comprehensive approach to characterizing the human p53 network that includes p53 levels, binding, expression and chromatin changes under diverse str...

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Detalhes bibliográficos
Main Authors: Menendez, Daniel, Nguyen, Thuy-Ai, Freudenberg, Johannes M., Mathew, Viju J., Anderson, Carl W., Jothi, Raja, Resnick, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753631/
https://ncbi.nlm.nih.gov/pubmed/23775793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt504
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