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Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells

Snail2 has an important role in the epithelial-mesenchymal transition (EMT) and tumor metastasis. Here, we report that Snail2 is highly expressed during TGF-β induced EMT in HL-7702 cells. Additionally, overexpression of Snail2 successfully promotes the migration and invasion of these cells, both in...

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Publicat a:Front Cell Dev Biol
Autors principals: Hu, Yue, Nie, Qing, Dai, Mingrui, Chen, Fangfang, Wu, Hui
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419474/
https://ncbi.nlm.nih.gov/pubmed/32850856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00752
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