Polyphenol-induced improvements in glucose metabolism are associated with bile acid signaling to intestinal farnesoid X receptor

INTRODUCTION: Bile acid (BA) biotransformation by gut bacteria impacts BA profile and signaling to nuclear receptors, such as the farnesoid X receptor (FXR) regulating glucose metabolism. Altered BA-FXR signaling was therefore investigated as a potential mechanism linking polyphenol-induced gut bact...

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Bibliografische gegevens
Gepubliceerd in:BMJ Open Diabetes Res Care
Hoofdauteurs: Tveter, Kevin M, Villa-Rodriguez, Jose A, Cabales, Alrick J, Zhang, Li, Bawagan, Fiona G, Duran, Rocio M, Roopchand, Diana E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2020
Onderwerpen:
Metabolism
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418775/
https://ncbi.nlm.nih.gov/pubmed/32771984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-001386
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