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AKR1B7 Is Induced by the Farnesoid X Receptor and Metabolizes Bile Acids
Although bile acids are crucial for the absorption of lipophilic nutrients in the intestine, they are cytotoxic at high concentrations and can cause liver damage and promote colorectal carcinogenesis. The farnesoid X receptor (FXR), which is activated by bile acids and abundantly expressed in entero...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Biochemistry and Molecular Biology
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024736/ https://ncbi.nlm.nih.gov/pubmed/21081494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181230 |
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