Transcriptional Regulation of the Intestinal Nuclear Bile Acid Farnesoid X Receptor (FXR) by the caudal-related Homeobox 2 (CDX2)

Farnesoid X receptor (FXR, NR1H4) is a bile acid-activated transcription factor that belongs to the nuclear receptor superfamily. It is highly expressed in the enterohepatic system, where it senses bile acid levels to consequently reduce their synthesis while inducing their detoxification. Bile acid...

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Hlavní autoři: Modica, Salvatore, Cariello, Marica, Morgano, Annalisa, Gross, Isabelle, Vegliante, Maria Carmela, Murzilli, Stefania, Salvatore, Lorena, Freund, Jean-Noel, Sabbà, Carlo, Moschetta, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192494/
https://ncbi.nlm.nih.gov/pubmed/25138215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.571513
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