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Transcriptional Regulation of the Intestinal Nuclear Bile Acid Farnesoid X Receptor (FXR) by the caudal-related Homeobox 2 (CDX2)

Farnesoid X receptor (FXR, NR1H4) is a bile acid-activated transcription factor that belongs to the nuclear receptor superfamily. It is highly expressed in the enterohepatic system, where it senses bile acid levels to consequently reduce their synthesis while inducing their detoxification. Bile acid...

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Main Authors: Modica, Salvatore, Cariello, Marica, Morgano, Annalisa, Gross, Isabelle, Vegliante, Maria Carmela, Murzilli, Stefania, Salvatore, Lorena, Freund, Jean-Noel, Sabbà, Carlo, Moschetta, Antonio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192494/
https://ncbi.nlm.nih.gov/pubmed/25138215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.571513
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