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Phosphorylation of cardiac myosin–binding protein-C contributes to calcium homeostasis

Cardiac myosin–binding protein-C (cMyBP-C) is highly phosphorylated under basal conditions. However, its phosphorylation level is decreased in individuals with heart failure. The necessity of cMyBP-C phosphorylation for proper contractile function is well-established, but the physiological and patho...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Kumar, Mohit, Haghighi, Kobra, Kranias, Evangelia G., Sadayappan, Sakthivel
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415972/
https://ncbi.nlm.nih.gov/pubmed/32554466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013296
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