Cardiac myosin binding protein c phosphorylation is cardioprotective

Cardiac myosin binding protein C (cMyBP-C) has three phosphorylatable serines at its N terminus (Ser-273, Ser-282, and Ser-302), and the residues' phosphorylation states may alter thick filament structure and function. To examine the effects of cMyBP-C phosphorylation, we generated transgenic m...

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Hlavní autoři: Sadayappan, Sakthivel, Osinska, Hanna, Klevitsky, Raisa, Lorenz, John N., Sargent, Michelle, Molkentin, Jeffrey D., Seidman, Christine E., Seidman, Jonathan G., Robbins, Jeffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Physical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636554/
https://ncbi.nlm.nih.gov/pubmed/17075052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607069103
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