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Cardiac Myosin Binding Protein-C Phosphorylation in a “Humanized” Mouse Heart
BACKGROUND: Cardiac myosin binding protein-C (cMyBP-C) phosphorylation modulates cardiac contractility. When expressed in cMyBP-C null (cMyBP-C((t/t))) hearts, a cMyBP-C phosphomimetic (cMyBP-C(AllP+)), rescued cardiac dysfunction and protected the hearts from ischemic-reperfusion (I/R) injury. Howe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2656413/ https://ncbi.nlm.nih.gov/pubmed/19237661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.798983 |
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