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Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice
The human cytochrome P450 family 11 subfamily B member 2 (hCYP11B2) gene encodes aldosterone synthase, the rate-limiting enzyme in the biosynthesis of aldosterone. In some humans, hCYP11B2 undergoes a unique intron conversion whose function is largely unclear. The intron conversion is formed by a re...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415971/ https://ncbi.nlm.nih.gov/pubmed/32540969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013047 |
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