All-trans-Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

PURPOSE: Extracellular accumulation of all-trans-retinaldehyde (atRAL), a highly reactive visual cycle intermediate, is toxic to cells of the outer retina and contributes to retinal and macular degenerations. However, the contribution of atRAL to retinal capillary function has not been studied. We h...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Dreffs, Alyssa, Lin, Cheng-Mao, Liu, Xuwen, Shanmugam, Sumathi, Abcouwer, Steven F., Kern, Timothy S., Antonetti, David A.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2020
Teme:
Retina
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415894/
https://ncbi.nlm.nih.gov/pubmed/32492112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.8
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