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All-trans-Retinaldehyde Contributes to Retinal Vascular Permeability in Ischemia Reperfusion

PURPOSE: Extracellular accumulation of all-trans-retinaldehyde (atRAL), a highly reactive visual cycle intermediate, is toxic to cells of the outer retina and contributes to retinal and macular degenerations. However, the contribution of atRAL to retinal capillary function has not been studied. We h...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Dreffs, Alyssa, Lin, Cheng-Mao, Liu, Xuwen, Shanmugam, Sumathi, Abcouwer, Steven F., Kern, Timothy S., Antonetti, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415894/
https://ncbi.nlm.nih.gov/pubmed/32492112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.8
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