Ischemia–reperfusion injury induces occludin phosphorylation/ubiquitination and retinal vascular permeability in a VEGFR-2-dependent manner

Retinal ischemia–reperfusion (IR) induces neurodegenaration as well as blood–retinal barrier (BRB) breakdown causing vascular permeability. Whereas the neuronal death has been extensively studied, the molecular mechanisms related to BRB breakdown in IR injury remain poorly understood. In this study,...

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Bibliographische Detailangaben
Hauptverfasser: Muthusamy, Arivalagan, Lin, Cheng-Mao, Shanmugam, Sumathi, Lindner, Heather M, Abcouwer, Steven F, Antonetti, David A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948134/
https://ncbi.nlm.nih.gov/pubmed/24398936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.230
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