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UGT2B10 genotype influences serum cotinine levels and is a primary determinant of higher cotinine in African American smokers

BACKGROUND: Cotinine is the most widely used biomarker of tobacco exposure. At similar smoking levels African Americans (AAs) have higher serum cotinine than Whites. UGT2B10-catalyzed cotinine glucuronidation impacts these levels, and AAs often have low UGT2B10 activity due to a high prevalence of a...

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Détails bibliographiques
Publié dans:Cancer Epidemiol Biomarkers Prev
Auteurs principaux: Sipe, Christopher J., Koopmeiners, Joseph S., Donny, Eric C., Hatsukami, Dorothy K., Murphy, Sharon E.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415710/
https://ncbi.nlm.nih.gov/pubmed/32532831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-20-0203
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