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Low cotinine glucuronidation results in higher serum and saliva cotinine in African American compared to White smokers

BACKGROUND: Tobacco exposure is often quantified by serum or saliva concentrations of the primary nicotine metabolite, cotinine. However, average cotinine concentrations are higher in African American (AA) compared to Whites with similar smoking levels. Cotinine is metabolized by UGT2B10 and CYP2A6,...

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Publicat a:Cancer Epidemiol Biomarkers Prev
Autors principals: Murphy, Sharon E, Sipe, Christopher J., Choi, Kwangsoo, Raddatz, Leah M., Koopmeiners, Joseph S., Donny, Eric C., Hatsukami, Dorothy K.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500430/
https://ncbi.nlm.nih.gov/pubmed/28264876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-16-0920
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