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Low cotinine glucuronidation results in higher serum and saliva cotinine in African American compared to White smokers

BACKGROUND: Tobacco exposure is often quantified by serum or saliva concentrations of the primary nicotine metabolite, cotinine. However, average cotinine concentrations are higher in African American (AA) compared to Whites with similar smoking levels. Cotinine is metabolized by UGT2B10 and CYP2A6,...

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Publicado en:Cancer Epidemiol Biomarkers Prev
Main Authors: Murphy, Sharon E, Sipe, Christopher J., Choi, Kwangsoo, Raddatz, Leah M., Koopmeiners, Joseph S., Donny, Eric C., Hatsukami, Dorothy K.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500430/
https://ncbi.nlm.nih.gov/pubmed/28264876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-16-0920
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