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Influence of UGT2B10 genotype on urinary excretion of NNAL-N-glucuronide by African American smokers

At similar smoking levels African American’s lung cancer risk is as much as twice that of whites. We hypothesized that racial/ethnic differences in UDP-glucuronosyltransferase (UGT)-catalyzed glucuronidation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a detoxication pathway for the toba...

詳細記述

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書誌詳細
出版年:Chem Res Toxicol
主要な著者: Murphy, Sharon E., vonWeymarn, Linda B., Parenteau, Marc, Stepanov, Irina, Tiirikainen, Maarit, Le Marchand, Loic, Park, Sungshim L.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058729/
https://ncbi.nlm.nih.gov/pubmed/29460622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00264
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