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Recurrent inversion toggling and great ape genome evolution

Inversions play an important role in disease and evolution but are difficult to characterize because their breakpoints map to large repeats. We increased by six-fold the number (n = 1,069) of previously reported great ape inversions using Strand-seq and long-read sequencing. We find that the X chrom...

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Bibliografske podrobnosti
izdano v:Nat Genet
Main Authors: Porubsky, David, Sanders, Ashley D., Höps, Wolfram, Hsieh, PingHsun, Sulovari, Arvis, Li, Ruiyang, Mercuri, Ludovica, Sorensen, Melanie, Murali, Shwetha C., Gordon, David, Cantsilieris, Stuart, Pollen, Alex A., Ventura, Mario, Antonacci, Francesca, Marschall, Tobias, Korbel, Jan O., Eichler, Evan E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415573/
https://ncbi.nlm.nih.gov/pubmed/32541924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0646-x
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