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Human-specific tandem repeat expansion and differential gene expression during primate evolution

Short tandem repeats (STRs) and variable number tandem repeats (VNTRs) are important sources of natural and disease-causing variation, yet they have been problematic to resolve in reference genomes and genotype with short-read technology. We created a framework to model the evolution and instability...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sulovari, Arvis, Li, Ruiyang, Audano, Peter A., Porubsky, David, Vollger, Mitchell R., Logsdon, Glennis A., Warren, Wesley C., Pollen, Alex A., Chaisson, Mark J. P., Eichler, Evan E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859368/
https://ncbi.nlm.nih.gov/pubmed/31659027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912175116
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