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High-resolution comparative analysis of great ape genomes

Genetic studies of human evolution require high-quality contiguous ape genome assemblies that are not guided by the human reference. We coupled long-read sequence assembly, full-length cDNA sequencing with a multi-platform scaffolding approach to produce ab initio chimpanzee and orangutan genome ass...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Kronenberg, Zev N., Fiddes, Ian T., Gordon, David, Murali, Shwetha, Cantsilieris, Stuart, Meyerson, Olivia S., Underwood, Jason G., Nelson, Bradley J., Chaisson, Mark J.P., Dougherty, Max L., Munson, Katherine M., Hastie, Alex R., Diekhans, Mark, Hormozdiari, Fereydoun, Lorusso, Nicola, Hoekzema, Kendra, Qiu, Ruolan, Clark, Karen, Raja, Archana, Welch, AnneMarie E., Sorensen, Melanie, Baker, Carl, Fulton, Robert S., Armstrong, Joel, Graves-Lindsay, Tina A., Denli, Ahmet M., Hoppe, Emma R., Hsieh, PingHsun, Hill, Christopher M., Pang, Andy Wing Chun, Lee, Joyce, Lam, Ernest T., Dutcher, Susan K., Gage, Fred H., Warren, Wesley C., Shendure, Jay, Haussler, David, Schneider, Valerie A., Cao, Han, Ventura, Mario, Wilson, Richard K., Paten, Benedict, Pollen, Alex, Eichler, Evan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6178954/
https://ncbi.nlm.nih.gov/pubmed/29880660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar6343
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