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Preclinical testing of AAV9-PHP.B for transgene expression in the non-human primate cochlea
In a number of mouse models of hereditary deafness, therapeutic transgene delivery to the cochlea and vestibular organs using adeno-associated viral vectors (AAVs) has shown striking rescue of hearing and balance. However, only a subset of AAV capsids have shown efficacy in transducing both inner ha...
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| Publicado no: | Hear Res |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415510/ https://ncbi.nlm.nih.gov/pubmed/32145977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2020.107930 |
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