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Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes

PURPOSE: Diabetic retinopathy (DR) is a leading cause of visual impairment. Müller cells in DR are dysfunctional due to downregulation of the inwardly rectifying potassium channel Kir4.1. Metformin, a commonly used oral antidiabetic drug, is known to elicit its action through 5′ adenosine monophosph...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Invest Ophthalmol Vis Sci
Egile Nagusiak: Alex, Alpha, Luo, Qianyi, Mathew, Deepa, Di, Rong, Bhatwadekar, Ashay D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Association for Research in Vision and Ophthalmology 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415324/
https://ncbi.nlm.nih.gov/pubmed/32572457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.46
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