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Metformin Corrects Abnormal Circadian Rhythm and Kir4.1 Channels in Diabetes
PURPOSE: Diabetic retinopathy (DR) is a leading cause of visual impairment. Müller cells in DR are dysfunctional due to downregulation of the inwardly rectifying potassium channel Kir4.1. Metformin, a commonly used oral antidiabetic drug, is known to elicit its action through 5′ adenosine monophosph...
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| Pubblicato in: | Invest Ophthalmol Vis Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Association for Research in Vision and Ophthalmology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7415324/ https://ncbi.nlm.nih.gov/pubmed/32572457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.46 |
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