PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins

BACKGROUND: The PIM family kinases promote cancer cell survival and motility as well as metastatic growth in various types of cancer. We have previously identified several PIM substrates, which support cancer cell migration and invasiveness. However, none of them are known to regulate cellular movem...

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Udgivet i:Cell Commun Signal
Main Authors: Santio, Niina M., Vainio, Veera, Hoikkala, Tuuli, Mung, Kwan Long, Lång, Mirka, Vahakoski, Riitta, Zdrojewska, Justyna, Coffey, Eleanor T., Kremneva, Elena, Rainio, Eeva-Marja, Koskinen, Päivi J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414696/
https://ncbi.nlm.nih.gov/pubmed/32771000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00618-6
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