Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth

Starting at birth, the immune system of newborns and children encounters and is influenced by environmental challenges. It is still not completely understood how γδ T cells emerge and adapt during early life. Studying the composition of T cell receptors (TCRs) using next-generation sequencing (NGS)...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Ravens, Sarina, Fichtner, Alina S., Willers, Maike, Torkornoo, Dennis, Pirr, Sabine, Schöning, Jennifer, Deseke, Malte, Sandrock, Inga, Bubke, Anja, Wilharm, Anneke, Dodoo, Daniel, Egyir, Beverly, Flanagan, Katie L., Steinbrück, Lars, Dickinson, Paul, Ghazal, Peter, Adu, Bright, Viemann, Dorothee, Prinz, Immo
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414158/
https://ncbi.nlm.nih.gov/pubmed/32690687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922588117
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