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Optimized renal transporter quantification by using aquaporin 1 and aquaporin 2 as anatomical markers: Application in characterizing the ontogeny of renal transporters and its correlation with hepatic transporters in paired human samples

Renal transporters, which are primarily located in the proximal tubules, play an important role in secretion and nephrotoxicity of drugs. The goal of this study was to characterize the age-dependent protein abundance of human renal transporters. A total of 43 human kidneys, 26 of which were paired w...

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Bibliografski detalji
Izdano u:AAPS J
Glavni autori: Li, Cindy Yanfei, Hosey-Cojocari, Chelsea, Basit, Abdul, Unadkat, Jashvant D., Leeder, J. Steven, Prasad, Bhagwat
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413827/
https://ncbi.nlm.nih.gov/pubmed/31297641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0359-1
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